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Targets Recommended: HCV Protease TLR

2

抑制剂 & 化合物

13

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Cat. No. Product Name Target Signaling Pathways
T6964 Resiquimod

R848,雷西莫特,S28463

HCV Protease; TLR Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Resiquimod (R848) 是一种 Toll 样受体7/8的激动剂,可诱导细胞因子上调。
T71325 ANA-773

ANA773 is a Toll-like Receptor 7 (TLR7) agonist prodrug with potential immunostimulating activity. Upon oral administration, ANA773 is metabolized into its active form that binds to and activates TLR7, thereby stimulating dendritic cells (DCs) and enhancing natural killer cell (NK) cytotoxicity. This activation results in the production of proinflammatory cytokines, including interferon alpha, and enhanced antibody-dependent cellular cytotoxicity (ADCC). TLR7 is a member of the TLR family, which...

化合物

Resiquimod
Cat.No: T6964
Synonym: R848,雷西莫特,S28463
Target: HCV Protease, TLR
ANA-773
Cat.No: T71325
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02515 Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

IFN-alphaJ,干扰素,IFNA-J,IFN-αJ,interferon, <...

Human HEK293 Cells
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P01567.
TMPY-04841 Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)

interferon, alpha 7,interfero...

Human P. pastoris (Yeast)
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A7R8C383.
TMPY-03612 PSME1 Protein, Human, Recombinant (His)

proteasome (prosome, macropain) activator subunit 1 (PA28

Human E. coli
PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunit...
TMPY-03610 PSME2 Protein, Human, Recombinant (His)

REGβ,proteasome (prosome, macropain) activator subunit 2 (PA...

Human E. coli
PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunit...
TMPY-02240 STAT1 Protein, Human, Recombinant (His & GST)

IMD31A,IMD31B,IMD31C,STAT91,CANDF7,signal transduce...

Human Baculovirus Insect Cells
STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands, including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. It is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob...

Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)

PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin-1,H23AG,PEM,CA 15...

Human HEK293 Cells
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1

Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1

Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ...
TMPK-01371 IGFBP-7 Protein, Human, Recombinant (hFc)

RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7

Human HEK293 Cells
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres...
TMPK-00395 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGF R1a,FGFR1 α,FGFR1 alpha,FGFR1 α (IIIc)

Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

FGFR1 α,FGFR1 alpha,FGF R1a,FGFR1 α (IIIc)

Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR,HBGFR,FLT-2,FGFB...

Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7.

重组蛋白

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02515
Species: Human
Expression System: HEK293 Cells
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)
Cat.No: TMPY-04841
Species: Human
Expression System: P. pastoris (Yeast)
PSME1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03612
Species: Human
Expression System: E. coli
PSME2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03610
Species: Human
Expression System: E. coli
STAT1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02240
Species: Human
Expression System: Baculovirus Insect Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
Cat.No: TMPY-06036
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00828
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00392
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00394
Species: Human
Expression System: HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01371
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00395
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00393
Species: Human
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
Cat.No: TMPY-06035
Species: Human
Expression System: HEK293 Cells
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